教师简介

教师简介

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许冰

个人简介

许冰,副教授,博士,硕士生导师。

2007-2012年:中国医科大学(本科)

2012-2015年:第四军医大学(硕士)

2015-2018年:空军军医大学(博士)

2018-2019年:西安交通大学(博士后)

2019年至今:91111威斯尼斯人app/91111威斯尼斯人app

主要研究方向:

1.非酒精性脂肪性肝病的机制研究

2.结肠癌转移的分子机制研究



承担的科研项目

2020   国家自然科学基金青年科学基金项目 

2019   中国博士后科学基金第65批二等面上资助


科研工作介绍

1. 通过构建非酒精性脂肪性肝病相关动物模型,探究炎症反应和不同细胞死亡方式在非酒精性脂肪性肝病进展过程中的作用及机制;

2. 筛选在结肠癌转移过程中被糖基化修饰的分子,探究其在结肠癌转移过程中的作用及机制。


主要研究成果

以通讯/共同通讯作者发表SCI论文5篇,总IF=24.94 分, 单篇最高IF=10.717分

以第一/共同第一作者发表SCI论文5篇,总IF=46.37 分, 单篇最高IF=18.946分


通讯/共同通讯作者文章 (5篇)

1. Nan Wu#, Mingzuo Jiang#, Haiming Liu#, Yi Chu#, Dan Wang, Jiayi Cao, Zhiyang Wang, Xin Xie, Yuying Han*, Bing Xu*. LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway. Cell Death and Differentiation. 2020 Jul 31. Online ahead of print. (通讯作者,IF=10.717)

2. Yuying Han#, Nan Wu#, Mingzuo Jiang#, Yi Chu#, Zhiyang Wang, Hao Liu, Jiayi Cao, Haiming Liu*, Bing Xu*, Xin Xie*. Long non-coding RNA MYOSLID functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-29c-3p in gastric cancer. Cell Proliferation. 2019 Sep 9:e12678. (共同通讯作者,IF=5.753)

3. Nan Wu#, Mingzuo Jiang#, Yuying Han#, Haiming Liu, Yi Chu, Hao Liu, Jiayi Cao, Qiuqiu Hou, Yu Zhao, Bing Xu*, Xin Xie*. O-GlcNAcylation promotes colorectal cancer progression by regulating protein stability and potential catcinogenic function of DDX5. Journal of Cellular and Molecular Medicine. 2019 Feb;23(2):1354-1362. (共同通讯作者,IF=4.486)

4. Nan Wu#, Yuying Han#, Haiming Liu#, Mingzuo Jiang, Yi Chu, Jiayi Cao, Junchao Lin, Yuanning Liu*, Bing Xu*, Xin Xie*. miR-5590-3p inhibited tumor growth in gastric cancer by targeting DDX5/AKT/m-TOR pathway. Biochemical and Biophysical Research Communications. 2018 Sep 10;503(3):1491-1497. (共同通讯作者,IF=2.705)

5. Mingzuo Jiang#, Nan Wu#, Xi Chen#, Weijie Wang, Yi Chu, Hao Liu, Wenjiao Li, Di Chen*, Xiaowei Li*, Bing Xu*. Pathogenesis of and major animal models used for nonalcoholic fatty liver disease. Journal of International Medical Research. 2019 Apr;47(4):1453-1466. (通讯作者,IF=1.287)


第一作者/共同第一作者文章(5 篇)

1. Bing Xu#, Mingzuo Jiang#, Yi Chu#, W eijie W ang#, Di Chen, Xiaowei Li, Zhao Zhang, Di Zhang, Daiming Fan, Yongzhan Nie, Feng Shao, Kaichun Wu*, Jie Liang*. Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in human and mice. Journal of Hepatology. 2018 04;68(4). (第一作者, IF=18.946)

2. Bing Xu#, Xiaowei Li#, Jipeng Yin#, Cong Liang, Lijuan Liu, Zhaoyan Qiu, Liping Yao, Yongzhan Nie, Jing Wang and Kaichun Wu*. Evaluation of 68 Ga-labeled MG7 antibody: a targeted probe for PET/CT imaging of gastric cancer. Scientific Reports. 2015 Mar 3;5:8626. (第一作者, IF=5.228)

3. Mingzuo Jiang#, Nan Wu#, Bing Xu#, Yi Chu#, Xiaowei Li, Song Su, Di Chen, Wenjiao Li, Yanting Shi, Xiaoliang Gao, Haohao Zhang, Zhao Zhang, Wei Du, Yongzhan Nie, Jie Liang, Daiming Fan. Fatty acid-induced CD36 expression via OGlcNAcylation drives gastric cancer metastasis. Theranostics. 2019; 9(18):5359-5373. (共同第一作者 , IF=8.579)

4. Mingzuo Jiang#, Bing Xu#, Xiaowei Li#, Yulong Shang#, Yi Chu, Weijie Wang, Di Chen, Nan Wu, Sijun Hu, Song Zhang, Mengbin Li, Kaichun Wu, Xiaoyong Yang, Jie Liang, Yongzhan Nie*, Daiming Fan*. O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit. Oncogene. 2019 Jan;38(3):301-316. (共同第一作者, IF=7.971)

5. Xiaowei Li#, Mingzuo Jiang#, Di Chen#, Bing Xu#, Rui Wang, Yi Chu, Weijie Wang, Lin Zhou, Zhijie Lei, Yongzhan Nie, Daiming Fan, Yulong Shang*, Kaichun Wu*, Jie Liang*. miR-148b-3p inhitis gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis. Journal of Experimental and Clinical Cancer Research.2018 Mar 27;37(1):71. (共同第一作者, IF=5.646)

获得的教学和科研表彰

许冰

所属部门: 91111威斯尼斯人app
职称: 副教授
荣誉: 硕士生导师
研究方向:

非酒精性脂肪性肝病的机制研究,结肠癌转移的分子机制研究

电子邮件: xubing@nwu.edu.cn